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Marie Stampe Ostenfeld Selected Research

Lu 28-179 (Siramesine)

5/2008Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation.
3/2007Vincristine induces dramatic lysosomal changes and sensitizes cancer cells to lysosome-destabilizing siramesine.
10/2005Effective tumor cell death by sigma-2 receptor ligand siramesine involves lysosomal leakage and oxidative stress.

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Marie Stampe Ostenfeld Research Topics

Disease

7Neoplasms (Cancer)
08/2017 - 10/2005
4Carcinoma (Carcinomatosis)
08/2017 - 03/2007
4Urinary Bladder Neoplasms (Bladder Cancer)
08/2017 - 03/2007
2Breast Neoplasms (Breast Cancer)
03/2007 - 10/2005
1Colorectal Neoplasms (Colorectal Cancer)
01/2016
1Lymphatic Metastasis
10/2014
1Prostatic Neoplasms (Prostate Cancer)
04/2014
1Carcinogenesis
09/2012

Drug/Important Bio-Agent (IBA)

4MicroRNAs (MicroRNA)IBA
08/2017 - 09/2012
3sigma-2 receptorIBA
05/2008 - 10/2005
3Lu 28-179 (Siramesine)IBA
05/2008 - 10/2005
3LigandsIBA
05/2008 - 10/2005
2Biomarkers (Surrogate Marker)IBA
01/2016 - 04/2014
2Proteins (Proteins, Gene)FDA Link
03/2014 - 03/2007
2CathepsinsIBA
05/2008 - 03/2007
2CaspasesIBA
03/2007 - 10/2005
1Epithelial Cell Adhesion MoleculeIBA
01/2016
1RNA (Ribonucleic Acid)IBA
10/2014
1Formaldehyde (Formol)FDA Link
09/2012
1ParaffinIBA
09/2012
1Cisplatin (Platino)FDA LinkGeneric
09/2012
1Untranslated RNA (Noncoding RNA)IBA
09/2012
1AminesIBA
05/2008
1Detergents (Detergent)IBA
05/2008
1Antineoplastic Agents (Antineoplastics)IBA
03/2007
1lens epithelium-derived growth factorIBA
03/2007
1HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
03/2007
1Antimitotic AgentsIBA
03/2007
1Vincristine (Oncovin)FDA LinkGeneric
03/2007
1Reactive Oxygen Species (Oxygen Radicals)IBA
10/2005
1ChromatinIBA
10/2005

Therapy/Procedure

3Therapeutics
05/2008 - 10/2005
1Prostatectomy (Retropubic Prostatectomy)
04/2014
1Drug Therapy (Chemotherapy)
09/2012